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NEWS RELEASES - via EurekAlert!

From the ashes of a failed pain drug, a new therapeutic path emerges

( Boston Children's Hospital) A surprising discovery about a failed pain drug -- and specifically, the pathway it targets, BH4 -- could have implications for autoimmunity and cancer. Neuroscientists at Boston Children's Hospital and immunologists from IMBA in Vienna report that BH4 also functions as a kind of immunological thermostat, raising and lowering the activity levels of T cells. Inhibiting BH4 could relieve atopic dermatitis, psoriasis, lupus, polyarthritis and inflammatory bowel disease; boosting it could help the immune system attack cancers.

Treated superalloys demonstrate unprecedented heat resistance

( DOE/Idaho National Laboratory) Researchers at Idaho National Laboratory have discovered how to make 'superalloys' even more super, extending useful life by thousands of hours. The discovery could improve materials performance for electrical generators and nuclear reactors.

DOE grant aimed at improving process to reduce nuclear fuel waste

( Penn State) An $800,000 grant from the US Department of Energy will allow Penn State researchers to investigate a new approach for removing rare-earth fission products from the molten salt baths where used nuclear fuel is electro-refined to recycle uranium and minimize nuclear waste.

NASA catches Tropical Cyclone Gaja's landfall

( NASA/Goddard Space Flight Center) Caught in the act of landfall, Tropical Cyclone Gaja was seen by NASA's Aqua satellite as it passed overhead and collected temperature information.

NSF funds research predicting gene mutations via computational algorithms

( Virginia Tech) Virginia Tech and Colorado State University researchers have been awarded a $1.52 million grant from the National Science Foundation (NSF) to develop new algorithms and mathematical models with the goal of predicting the effects of novel combinations of gene mutations in living cells. They will apply this computational framework to models of cell growth and division in budding yeast.

Insilico Medicine to present 'Cure a disease in a year' challenge at BioDataWorld 2018

( InSilico Medicine, Inc.) Insilico Medicine announces to present its research and introduce the 'Cure a disease in a year' program at the World's leading congress for big data in precision medicine -- Biodata World Congress 2018.

IU Philanthropic Venture Fund invests in regenerative medicine company Vascugen

( Indiana University) Vascugen Inc., which licenses intellectual property from the Indiana University Innovation and Commercialization Office, has received an investment from the IU Philanthropic Venture Fund. Vascugen is a regenerative medicine company.

New way to look at cell membranes could change the way we study disease

( University of Oxford) Researchers have developed a new technique to analyse cell membrane proteins in situ which could revolutionise the way in which we study diseases, such as cancer, metabolic and heart diseases.

Earthquake researchers finalists for supercomputing prize

( University of Tokyo) A team of researchers from the University of Tokyo and RIKEN in Japan were finalists for the coveted Gordon Bell Prize for outstanding achievements in high-performance computing, praised for their simulation of earthquake physics in complex urban environments.

Playing high school football changes the teenage brain

( University of California - Berkeley) A single season of high school football may cause microscopic changes in the structure of the brain, according to a new study by researchers at the University of California, Berkeley, Duke University and the University of North Carolina at Chapel Hill. A new type of magnetic resonance imaging (MRI) revealed significant changes in the structure of the grey matter in the front and rear of the brain and changes to structures deep inside the brain.

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